This analog has been engineered with the express purpose of increasing biological activity. IGF-1 Long[R3] is significantly more potent than IGF-1 in vitro and in vivo. The enhanced
potency is due to the markedly decreased binding of IGF-1 Long[R3] to all IGF binding proteins. These binding proteins normally inhibit the biological actions of IGFs. IGF-1 stands for insulin-like growth factor. It is a natural substance that is produced in the human body and is at its highest natural levels during puberty. During puberty IGF-1 is the most responsible for the natural muscle growth that occurs during these few years. There are many different things that IGF-1 does in the human body.
Among the effects the most positive are:
increased amino acid transport to cells
increased glucose transport
increased protein synthesis
decreased protein degradation
increased RNA synthesis.
When IGF-1 is active it behaves differently in different types of tissues. In muscle cells proteins and associated cell components are stimulated. Protein synthesis is increased along with amino acid absorption. As a source of energy, IGF-1 mobilizes fat for use as energy in adipose tissue. In lean tissue, IGF-1 prevents insulin from transporting glucose across cell membranes. As a result the cells have to switch to burning off fat as a source of energy. IGF-1 also mimic’s insulin in the human body. It makes muscles more sensitive to insulin’s effects, so if you are a person that currently uses insulin you can lower your dosage by a decent margin to achieve the same effects, and as mentioned IGF-1 will keep the insulin from making you fat. Perhaps the most interesting and potent effect IGF-1 has on the human body is its ability to cause hyperplasia, which is an actual splitting of cells. Hyperplasia is significantly different from Hypertrophy. Hypertrophy is simply an increase in the size of muscle cells. After puberty the human body has a set number of muscle cells, and Hypertrophy is to increase the size of these muscle cells. But IGF-1 is able to cause hyperplasia which actually increases the number of muscle cells present in the tissue. So in a way IGF-1 can actually change your genetic capabilities in terms of muscle tissue and cell count. IGF-1 proliferates and differentiates the number of types of cells present. At a genetic level it has the potential to alter an individuals capacity to build superior muscle density and size.
Regular IGF-1 only has a half-life of about 10-20 minutes in the human body and is quickly destroyed. The most effective IGF analog form of all is IGF-1 L[R3]. Because of its chemical alteration and the amino acid changes, IGF-1 L[R3] can avoid binding to proteins in the human body and so to have a much longer half life, around 20-30 hours.
Although IGF-1 is a very powerful muscle builder and fat burner, It is considered IGF-1 L[R3]to be 2-3 times more effective.
IGF-1 L[R3] cycles should be kept to 4-6 weeks with 4-6 weeks off in-between. IGF-1 L[R3] is considerably more powerful than HGH and this should be reflected in dosage. It is recommended a dosage of 50-80 mcg per day. It should be better to take this dosage every day for 4 weeks. This must be followed by a 4 week off. This dosage can be divided in two: one after waking up in the morning and the other before to go to bed at night. Or some prefer to take it all just after the workout., the sooner the better. In any case the dosage must not exceed 100mcg!!!
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- Product Code: 1mg
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